Endocrine Abstracts

Purpose: To investigate the kinetics of adrenocorticotropin (ACTH) following oral metyrapone administration and describe differences between ACTH-deficient and non ACTH-deficient subjects.Methods: Patients from a tertiary endocrine center at a University Hospital in Munich, Germany, were tested. Metyrapone (Metopirone, HRA Pharma, France) was administered with a dosage of 40 mg/kg bodyweight at 0800 h. Consecutive levels of ACTH were determined at 0, 60,...

Objectives: We report on a case of a 32-year-old patient with urticaria pigmentosa, the cutaneous form of mastocytosis, since the age of 13. A bone marrow biopsy revealed systemic mastocytosis disease. In 2005, after a minor trauma, the patient had an X-ray of the spine which showed a new fracture of the thoracic vertebrae 3–4. Further DXA examination of the bone mineral density showed osteoporosis (T-Score −2.8 lumbar vertebrae; right/left femur −1.0/&...